Bethesda units (BUs) show how strong your inhibitor is. The strength is called your titer. The higher your titer, the less likely it is that normal factor will work.



    When there is no inhibitor (0 BU), all of the factor you infuse reaches the bleed.

    As your titer rises, less factor reaches the bleed. The inhibitor "inhibits" the factor from working. The higher the titer, the more factor you need to stop a bleed.

    Once your titer reaches 5 BUs, almost no factor reaches the bleed. This means that normal factor probably will not work. People with hemophilia with high titers need bypassing agents instead of replacement factor.

    Learn about therapies that help stop bleeds fast. Read more

    You always want your titer to be low.


Next: Stopping bleeds quickly>